WebJun 28, 2024 · These CTCF–CTCF interactions mostly initiate chromatin loops when the CTCF-bound sites are in a convergent (i.e. forward and reverse) orientation (23, 24) rather than divergent orientation, which has been mostly observed at non-looped TAD boundaries (20, 24). CTCF also co-ordinates chromatin architecture in concert with the cohesin … WebMay 27, 2024 · In animals, loops and other features of three-dimensional chromatin architecture rely on CCCTC-binding factor (CTCF). Plants do not encode CTCF orthologs, and thus the mediator of these long-range interactions has been mysterious.
Role of the cellular factor CTCF in the regulation of bovine …
WebCTCF is a nuclear protein initially discovered for its role in enhancer-promoter insulation. It has been shown to play a role in genome architecture and in fact, its DNA binding sites are enriched at the borders of chromatin domains. Recently, we showed that depletion of CTCF impairs the DNA damage response to ionizing radiation. To investigate the relationship … WebSep 21, 2024 · Insulator activity in our assay system depends upon the ability of the three non-plant sequences to bind Rap1-like, CTCF-like, and Su(Hw)-like plant proteins. Database searches for CTCF have not found a homolog in several plant genomes including A. thaliana, Vitis vinifera (Heger et al. 2009) and eight other species (Heger et al. 2012). free printable easter crossword puzzles
Measuring cell fluorescence using ImageJ — The Open Lab Book …
WebCTCF is listed in the World's largest and most authoritative dictionary database of abbreviations and acronyms CTCF - What does CTCF stand for? The Free Dictionary WebSep 27, 2024 · CTCF is a conserved DNA- and RNA-binding protein with roles in genome folding and transcriptional regulation. Two recent studies investigated how CTCF knockout perturbs genome biology and derails ... WebCTCF, histone H3K27me3, Rad21, and Pc ChIP-seq profiles are aligned above the map. TADs are indicated by yellow outlines. ( B) Hi-C contact map at 500-bp resolution of a region of chromosome 2L shows a small network of chromatin loops (cyan circles) that align with Pc ChIP-seq peaks. free printable easter craft