WebMay 25, 2016 · Fexofenadine HCl (FFN) is a second-generation nonsedating histamine H 1 receptor antagonist extensively used in seasonal allergic rhinitis. The usual dose for adults is 60 mg two times a day or 180 mg once a day. The half life of the drug is 14.4 h and the oral bioavailability is 30–41 % (Product Information: Allegra reviewed 1/ 2000 ). WebThe DSC traces (Figure 1C and Table 1) representing reverse heat flow signals revealed the same trend among different HPMC samples. The HPMC samples exhibited obvious …
Thermal analysis of hydroxypropylmethylcellulose and methylcellulose ...
WebJul 31, 2014 · A HPLC method was used in determination of drug content of films and analysis of samples in drug release studies using HPLC (Waters 2695 series, USA, PDA Detector (Waters 2996 PDA, USA)) and an integrator (Empower). WebMar 5, 2024 · The results of FT-IR, XPRD, DSC and 1H NMR analysis show the formulation of inclusion complexes. In conclusion, the interaction occurrs between fenofibrate and HP-β-CD in the complexes, and the existence of HPMC effectively improves the complexation efficiency and stability constant. ntsb accident and incident data system
Characterisation of the glass transition of HPMC using
WebMar 25, 2024 · Differential scanning calorimetry (DSC Perkin Elmer USA) was used to analyze the distinct thermal behavior of polymers (AG and HPMC), drug (OND), and buccal films. The scanning was done over a wide range of temperature (20°C to 300°C) for known quantity of each samples with heating at proportion of 10°C/min using nitrogen gas purge … WebHypromellose (HPMC) is an excellent polymer for the formation of solid dispersions with APIs. HPMC is a water soluble polymer that can help maintain stable solid dispersions … WebThe utility of hypromellose acetate succinate (HPMCAS), a cellulosic enteric coating agent, as a carrier in a solid dispersion of nifedipine (NP) was evaluated in comparison with other polymers, including hypromellose (HPMC), hypromellose phthalate (HPMCP), methacrylic acid ethyl acrylate copolymer (MAEA), and povidone (PVP). ntsb 85th percentile