Hcc1806 mutation

Author: oema

August undefined, 2024

WebMay 3, 2024 · CRL-2335™ HCC1806 Primary acantholytic squamous cell carcinoma primary CDKN2A KDM6A STK11 TP53 homozygous homozygous homozygous homozygous c.1_471del471 ... (Catalogue of Somatic Mutations in Cancer) database and website. Br J Cancer, 91,355-358. ATCC and The Sanger Institute provide these data in … WebNov 3, 2024 · For in vivo Dox-induced TRIM37 upregulation studies, mice bearing approximately 200 mm 3 HCC1806 tumors weight matched animals were randomly assigned into groups and injected with 2 mg/kg Dox. Tumors were harvested 24 hours following Dox treatment.

Gene Set - HCC1806

WebCRL-2335™ HCC1806 Primary acantholytic squamous cell carcinoma primary CDKN2A homozygous c.1_471del471 p.0? KDM6A homozygous c.444_564del121 p.0 STK11 … WebCCLE Name: HCC1806_BREAST. COSMIC ID: 907047. Sanger ID: 1317. Cellosaurus RRID: CVCL_1258. Aliases: HCC1806. Disease Breast Cancer ... Expression 21Q3 Public Copy Number 21Q3 Public Hotspot Mutations Damaging Mutations Other Non-conserving Mutations Mutation 21Q3 Public Methylation (1kb upstream TSS) Copy Number … melina thielen

Triple Negative Breast Cancer Cell Lines with TP53 Mutations are ..…

Web23 rows · HCC1806 Alternative Names: HCC-1806 LINCS ID: LCL-1960 Alternative ID: CLO_0003644: Parent Cell Line: Reference Source: ATCC CRL-2335: Organism: Homo … WebJan 11, 2024 · Proliferation assays on the engineered a HCC1395, b HCC1806, and c SUM159 cells with 0.5 µg/ml Dox-induced expression of MAPK4 (iMAPK4) or control (iCtrl). The cells were also treated with 1 µM ... WebMay 24, 2024 · TP53 mutations in tumor cells increased the level of hypoxia-induced factor-1α (HIF-1α) and augmented HIF-1α-dependent transcriptional activation of the VEGF gene in response to hypoxia 33. melina thier

HCC1806 DepMap Cell Line Summary

WebMar 15, 2024 · Combined SNAT1 silencing and GCN2 inhibition significantly inhibited growth of ASCT2ko HCC1806 cells, but not of ASCT2ko 143B cells. Similarly, pharmacological inhibition of l-type amino acid transporter 1 (LAT1) and GCN2 significantly inhibited growth of ASCT2ko HCC1806 cells, but not of ASCT2ko 143B cells. WebHCC1806. Depmap ID: ACH-000624. CCLE Name: HCC1806_BREAST. COSMIC ID: 907047. Sanger ID: 1317. Cell Line Passport: SIDM00875. Cellosaurus RRID: … melina the wrestlerWebSep 1, 2015 · Over 80% of TNBC cells have a mutated p53 tumor suppressor gene. The p53 pathway is responsible for a cells arrest or death response to stress. Here we show … melina thomsen

"WebJun 1, 2024 · In parallel, HCC1806 and MDA-MB-231 cells were cultured in complete medium containing drug vehicle (DMSO) alone for the same period of time (28 days). RNA-Sequencing (RNA-Seq), Assay for Transposase-Accessible Chromatin Sequencing (ATAC-Seq), and DNA methylation arrays were performed after the 4 cycles. " - Hcc1806 mutation

Hcc1806 mutation

Breast Tumor Cells with PI3K Mutation or HER2 Amplification Are ...

WebAug 26, 2008 · (A) HCC1806 and T47D cells were treated with 1 µM AKTi-1/2 for the indicated times and cell lysates were immunoblotted with the indicated antibodies. (B) HCC1806 and T47D cells were treated with 1 …

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WebOct 11, 2024 · In both the HR + BC HCC1428 and CCNE amp TNBC HCC1806 models, the CDK2 50% occupancy concentration (OC 50) ... These mutations appear to arise in patients that respond well to these therapies and are not necessarily drivers of poor response (O'Leary et al., 2024). Validation of a CDK2-driven mechanism of CDK4/6 … WebHCC1806. We exposed the TNBC cell lines HCC70 and HCC1806, and a normal breast cell line AG11132 to the chemotherapeutics staurosporine, Actinomycin D, and doxorubicin …

WebNov 11, 2013 · High-grade serous ovarian cancers (HGSCs) are characterized by a high frequency of TP53 mutations, BRCA1/2 inactivation, homologous recombination dysfunction, and widespread copy number changes. Cyclin E1 (CCNE1) gene amplification has been reported to occur independently of BRCA1/2 mutation, and it is associated … WebDec 13, 2024 · HEK-293T cells for lentiviral packaging and the TNBC cell lines HCC1806, MDA436, MDA468, and MDA231 were obtained from the ATCC and cultured as described previously ( 30, 40 ). The TNBC cell lines SUM149 and SUM159 were obtained from Asterand Bioscience and cultured in Ham F12 medium with 5% FBS, 5 μg/mL insulin, …

WebJun 1, 2024 · BT549, HCC38, HCC1806, HCC1937, HCC1599, BT20, and HCC1395 cells were grown in Roswell Park Memorial Institute 1640 (RPMI1640) medium (Sigma-Aldrich … WebHCC1806 Gene Set Genes 86 genes mutated in the HCC1806 cell line from the CCLE Cell Line Gene Mutation Profiles dataset. Show entries Filter Showing 1 to 20 of 86 entries Previous 1 2 3 4 5 Next Rouillard AD, Gundersen GW, Fernandez NF, Wang Z, Monteiro CD, McDermott MG, Ma'ayan A.

WebMar 19, 2024 · HCC1806 cells stably expressing shAMPKα1-1 (shAα1-1), shAMPKα1-2 (shAα1-2), or Hs578T cells stably expressing wild-type flag-AMPKα1 (Aα1-WT), constitutively active mutation flag-AMPKα1-T172D (Aα1-CA) were subjected to Western blot analyses ( G and J) or transwell assays for cell invasion ( H and K ). (Scale bars, H …

WebAug 4, 2024 · Characterization of TNBC cell lines. Nine cell lines representing the six molecular subtypes of TNBC [] were characterized for their expression of cellular markers.Basal-like cell lines (BL1: MDA-MB-468; BL2: HCC70, HCC1806) had much higher IGFBP-3 and EGFR expression than cells of the other subtypes (Fig. 1a-d).These cell … narrow ridge crosswordWebJan 11, 2024 · Proliferation assays on the engineered a HCC1395, b HCC1806, and c SUM159 cells with 0.5 µg/ml Dox-induced expression of MAPK4 (iMAPK4) or control (iCtrl). The cells were also treated with 1 µM... melina thoumazetWebJun 1, 2024 · BT549, HCC38, HCC1806, HCC1937, HCC1599, BT20, and HCC1395 cells were grown in Roswell Park Memorial Institute 1640 (RPMI1640) medium (Sigma-Aldrich … melina tholler