Refractoriness medical definition

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August undefined, 2024

WebJan 31, 2024 · The word “refractory” in general use means stubborn or intractable, and in medicine it is specifically applied to disease that does not respond to treatment. Refractory cancer refers to cancer that may be resistant at the beginning of treatment, or becomes resistant during treatment. WebApr 2, 2024 · 4. Resting and Action Potentials in Excitable Cells. The absolute refractory period refers to that period of time after an action potential when it is impossible to initiate a new action potential no matter how large the stimulus. This is a relatively short period of time that varies from cell to cell but roughly occurs approximately 1/2 to 1 ...

Platelet refractoriness - Wiley Online Library

Webre·frac·to·ry ( rĕ-frak'tŏr-ē) 1. Resistant to treatment, as of a disease. Synonym (s): intractable (1) , obstinate (2) . 2. Synonym (s): obstinate (1) . [L. refractarius, fr. refringo, pp. -fractus, … Webdis·ease (dĭ-zēz′) n. 1. An abnormal condition of a part, organ, or system of an organism resulting from various causes, such as infection, inflammation, environmental factors, or genetic defect, and characterized by an identifiable group of signs, symptoms, or both. 2. A condition or tendency, as of society, regarded as abnormal and harmful. 3 ... beban studi kelas karyawan jakarta timur

Refractoriness - definition of refractoriness by The Free Dictionary

http://www.fasthealth.com/dictionary/r/refractoriness.php WebAug 28, 2014 · It is still being debated what should be the key parameter of a definition of refractoriness (e.g., unresponsiveness to treatment, high frequency, severe disability or all of these features) ... medical cost reimbursement, screening tool for invasive treatment or implantable devices. With the need of minimizing the risk of a misdiagnosis we ... Webre·frac·to·ry ( rĕ-frak'tŏr-ē) 1. Resistant to treatment, as of a disease. Synonym (s): intractable (1) , obstinate (2) . 2. Synonym (s): obstinate (1) . [L. refractarius, fr. refringo, pp. -fractus, to break in pieces] Medical Dictionary for the Health Professions and Nursing © Farlex 2012 re·frac·to·ry ( rĕ-frak'tŏr-ē) beban sumbu

$Platelet Refractoriness AACC.org$

Refractory chronic migraine: a Consensus Statement on clinical ...

Webadj. 1. Showing or characterized by obstinate resistance to authority or control: refractory children; refractory behavior. 2. Difficult to melt or work; resistant to heat: a refractory … WebRefractoriness. a short-term decrease in the excitability of nervous or muscle tissue occurring immediately after the manifestation of action potential. It can be detected by … beban subsidi bbmWebIn conclusion, platelet transfusion refractoriness requires 2 or more inappropriate responses to platelets as defined by below normal PPR or CCI. Platelet transfusion refractoriness is … beban sumbu adalah

"WebOct 22, 2024 · The use of allogeneic hematopoietic stem cell transplantation (allo-HSCT) continues to rapidly increase worldwide. 1 However, graft-versus-host disease (GVHD) remains a major limitation of a successful allo-HSCT. 2,3 Up to 50% of patients will develop acute GVHD, despite immunosuppressive prophylaxis, 3-5 and this complication is a … " - Refractoriness medical definition

Refractoriness medical definition

$Refractory disease - definition of Refractory ... - The Free Dictionary$

WebFeb 13, 2024 · However, the definition of refractory, if it includes insufficient response to TPO agents, describes a group with more severe and difficult-to-treat disease. The biology of refractory ITP is largely unexplored and includes oligoclonality, lymphocyte pumps, and other possibilities. ... the mechanism of refractoriness in oligo/monoclonal patients WebA failure of circulating platelet levels to rise after platelet transfusion. Alloimmunization against platelet antigens, disseminated intravascular coagulation, fever, hypersplenism, and sepsis are among the potential causes. A typical platelet transfusion should normally raise platelet counts by more than 20,000 platelets/microliter.

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WebDec 4, 2024 · Refractoriness can be caused by immune and nonimmune factors, with nonimmune factors responsible for 60% to 80% of cases. 1 Immune factors, which play a … WebSep 22, 2016 · An International Working Group (IWG) defined refractory ITP as disease that does not respond to or relapses after splenectomy and that requires treatment to reduce the risk of clinically significant bleeding. 2 The American Society of Hematology ITP Guidelines endorsed this definition as a means of identifying the most severely affected patients. …

WebPlatelet transfusion refractoriness. Platelet transfusion refractoriness is the repeated failure to achieve the desired level of blood platelets in a patient following a platelet transfusion. The cause of refractoriness may be either immune or non-immune. Among immune-related refractoriness, antibodies against HLA antigens are the primary cause. Webrefractoriness -t (ə-)rē-nəs noun Medical Definition refractory adjective re· frac· to· ry ri-ˈfrak-t (ə-)rē 1 : resistant to treatment or cure a refractory fulminant lesion had disease that …

WebThe meaning of REFRACTORINESS is the insensitivity to further immediate stimulation that develops in irritable and especially nervous tissue as a result of intense or prolonged stimulation. the insensitivity to further immediate stimulation that develops in irritable … Synonyms for REFRACTORINESS: rebellion, recalcitrance, rebelliousness, … WebApr 12, 2024 · The refractory period is the time after an action potential is generated, during which the excitable cell cannot produce another action potential. There are two subphases of this period, absolute and relative refractoriness. Absolute refractoriness overlaps the depolarization and around 2/3 of repolarization phase.

WebMay 12, 2024 · Definition – Platelet refractoriness is defined as a platelet count increment less than expected after at least two platelet transfusions. Quantitative definitions may be …

WebJul 20, 2015 · Definition Platelet refractoriness can represent a significant clinical problem that complicates provision of platelet transfusions, and which may be associated with adverse clinical outcomes and increased health care costs. beban statik ekivalen adalahWebApr 13, 2024 · noun : the period immediately following the firing of a nerve fiber when it cannot be stimulated no matter how great a stimulus is applied called also absolute refractory phase compare relative refractory period Dictionary Entries Near absolute refractory period absolute humidity absolute refractory period absolute zero See More … beban studi kuliah kelas karyawan regulerWebImportantly, refractoriness in cells with reduced E m can outlast voltage recovery of the action potential (i.e., the cell can still be refractory or partially refractory after the resting E m returns to its most negative value). View chapter Purchase book Temperature and Excitable Membranes☆ M. Vornanen, in Reference Module in Life Sciences, 2024 disable java auto update